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The best guest houses in Santa Cruz Region

Check out our selection of great guest houses in Santa Cruz Region

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Review Score

Wonderful: 9+ Very Good: 8+ Good: 7+ Pleasant: 6+
Our top picks Lowest Price First Star rating and price Top reviewed

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Hostel Serena

Samaipata

Hostel Serena in Samaipata offers free WiFi and private parking on site, the hostel is open 24 hours per day.

We can arrange your private taxi from the airport straight to the hostel if you want, for a cheap price if you want.

Hostel Serena has been welcoming Booking.com guests since Dec 27, 2016 -- Beautiful hostel that feels more like a family home. The owner is super nice and friendly, really nice common areas to meet other travellers, huge kitchen to cook, beautiful views out over the valley, lots of walks to do nearby, heaps of games, big garden space to chill out in, super clean and just a really nice vibe. Highly recommend staying here!

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9.3
Wonderful
424 reviews
Price from
$18
per night

Posada Guasu

Samaipata

Located in Samaipata, 9.3 km from Samaipata Fort, Posada Guasu provides accommodation with a garden, private parking and a shared lounge. The accommodation features room service, a 24-hour front desk and organising tours for guests.

The inn offers certain rooms with garden views, and the rooms come with a patio. At Posada Guasu each room comes with bed linen and towels. This place was amazing. The host was beautiful, nice, and very helpful. She even went out of her way to get us a fan for our room. She cooked breakfast for us, which was delicious. And even helped us negotiate a taxi to get back to Santa cruz. If you're going to samapati, check out this cute little b and b with a personal touch.

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9.3
Wonderful
253 reviews
Price from
$18.18
per night

Hostal Backpackers Travelero

Santa Cruz de la Sierra

Situated just less than 1 km from Arenal Park, Hostal Backpackers Travelero offers accommodation in Santa Cruz de la Sierra with access to an outdoor swimming pool, a garden, as well as a 24-hour front desk. The property has pool views and is 1.2 km from 24th of September Metropolitan Plaza and 1.4 km from Sacred Art Museum. The guest house features rooms with air conditioning, free private parking and free WiFi. This one of the best hostels I have every stayed at. It has a great atmosphere, the breakfast was great and filling. The most amazing part was the staff, literally everyone that works there is so kind and helpful! The older gentleman that works in the afternoon was so kind and friendly. I wish he was my real dad. Also the pool is pretty awesome

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8.9
Excellent
473 reviews
Price from
$11
per night

Andoriña Hostal - Bed & Breakfast

Samaipata

Located in Samaipata, 9.1 km from Samaipata Fort, Andoriña Hostal - Bed & Breakfast provides accommodation with a garden, free WiFi, a shared kitchen, and luggage storage space. The property has city and inner courtyard views. The guest house features family rooms. The perfect stay. I would go back right now. Everything from the staff to the place itself was great. Don't miss it if you go to Samaipata.

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8.8
Excellent
221 reviews
Price from
$12.40
per night

Fonda Amboró

Samaipata

With a private bathroom equipped with a shower and free toiletries, units at the guest house also offer free WiFi, while selected rooms come with a terrace.

Buffet and continental breakfast options with pancakes, fruits and juice are available daily at the guest house. Beds were very good, spacious bedrooms, good shower and bathroom, fully equipped kitchen, delicious breakfast with homemade bread and jam, very nice attention of Adrian.

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8.6
Excellent
47 reviews
Price from
$34
per night

Casa Rural Doña Blanca

Samaipata

Situated in Samaipata and only 10 km from Samaipata Fort, Casa Rural Doña Blanca features accommodation with mountain views, free WiFi and free private parking. The property features garden views. The guest house has family rooms. The place is big and has a very nice view. It also has parking space and it is just a few blocks from the city center. We had a nice stay overall.

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8.4
Very Good
8 reviews
Price from
$28.60
per night

Casa Sayana

Samaipata

Casa Sayana provides a garden, as well as accommodation with a kitchen in Samaipata, 10 km from Samaipata Fort. Featuring mountain and garden views, this guest house also provides guests with free WiFi. The guest house has private entrance. Maria is very friendly, we had a great night with a fire and other guests of the hostel.

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7.8
Good
133 reviews
Price from
$8
per night

La Casona

Santa Cruz de la Sierra

At the guest house, units are fitted with a wardrobe, a flat-screen TV, a private bathroom, bed linen and towels.

Popular points of interest near the guest house include Arenal Park, Sacred Art Museum and Metropolitan Cathedral. The nearest airport is Viru Viru International, 14 km from La Casona, and the property offers a paid airport shuttle service.

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10
Exceptional
1 reviews
Price from
$30
per night

Hostal Plaza de la Concordia

Santa Cruz de la Sierra

Hostal Plaza de la Concordia is set in Santa Cruz de la Sierra, 400 metres from Metropolitan Cathedral, 400 metres from 24th of September Metropolitan Plaza, and 1.1 km from Arenal Park. The air-conditioned accommodation is 200 metres from Sacred Art Museum. The guest house features family rooms.

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7
Good
3 reviews

Amaca Hostal

Santa Cruz de la Sierra

Amaca Hostal is set in Santa Cruz de la Sierra, 300 metres from Sacred Art Museum, 400 metres from Metropolitan Cathedral, as well as 400 metres from 24th of September Metropolitan Plaza. Boasting a 24-hour front desk, this property also provides guests with a sun terrace. The guest house offers rooms with air conditioning, free private parking and free WiFi.

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7.9
Good
10 reviews
Price from
$11
per night

Most booked guest houses in Santa Cruz Region this month

FAQs about guest houses in Santa Cruz Region

  • Many families visiting Santa Cruz Region loved staying at Casa Rural Doña Blanca, Hostel Serena, and Andoriña Hostal - Bed & Breakfast.

  • Hostel Serena, Hostal Backpackers Travelero, and Andoriña Hostal - Bed & Breakfast are some of the popular guest houses in Santa Cruz Region.

  • Most guest houses on Booking.com offer free cancellation.

  • The average price per night for a guest house in Santa Cruz Region for this weekend is $53, based on current Booking.com prices.

  • There are 17 guest houses in Santa Cruz Region you can book on Booking.com.

  • We make it quick and easy to book a guest house in Santa Cruz Region. Here’s what we offer:

    • Free cancellation on most stays
    • We Price Match
    • 24/7 customer support in 40+ languages

  • Couples traveling in Santa Cruz Region loved staying at Hostel Serena, Andoriña Hostal - Bed & Breakfast, and Fonda Amboró.

  • Hostal Backpackers Travelero, Andoriña Hostal - Bed & Breakfast, and Hostel Serena have received great reviews from guests in Santa Cruz Region about the views from these guest houses

Guest Houses that guests love in Santa Cruz Region