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Stay in Santa Cruz Region's best hotels!

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Wonderful: 9+ Very Good: 8+ Good: 7+ Pleasant: 6+
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Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar. The location, the staff, the style, the room and THE BREAKFAST! Everything really got me. I want to go back!

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9.1
Wonderful
1,108 reviews
Price from
$98.83
per night

Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,... Very comfortable hotel. Bed is soft, room is spacious, shower is perfect, the pool is nice, staff are helpful and location is great.

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9.1
Wonderful
587 reviews
Price from
$99
per night

Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace. Really loved the place. It's very cozy, quite and peaceful. I felt like i've visited my aunt, the ambience is very warm and homely. Perfect example of slow living. Thank you

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9.3
Wonderful
421 reviews
Price from
$39.60
per night

Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge. We loved the charm, comfort and friendly, helpful staff.

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9.5
Exceptional
206 reviews
Price from
$87
per night

Conveniently located only a 10-minute walk from Ventura Shopping Center, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. Fabulous staff and service. Wonderful amenities. Large room with plenty of lounging space and a comfortable bed and pillows. Linens were the best. Super clean. I would definitely stay here again. Thank you!

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9.4
Wonderful
433 reviews
Price from
$135
per night

Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available. Recently fully refurbished, the high standards and professionalism of the staff were only matched by their friendliness and helpfulness. Superb location, restaurants nearby. We stayed 14 nights, a fantastic 5 star experience in the middle of Santa Cruz.

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9.3
Wonderful
214 reviews
Price from
$121.50
per night

Located in Santa Cruz de la Sierra, a 19-minute walk from Güembé Biocentre and Guazú Ivaga Park, Hotel By Armonía Santa Cruz has accommodations with an outdoor swimming pool, free private parking, a... Very friendly and caring staff, absolutely everyone were very nice and friendly with us. We enjoyed the breakfast - we got it served, very fast, - it was very ample and nutritious; the swimming pool was warm, clean and deep enough; the interior as well as the exterior were fantastic, we enjoyed the garden and the location too - it was very quiet. Good wifi, excellent spacious shower room.

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9.4
Wonderful
73 reviews
Price from
$76.50
per night

Located in San Ignacio de Velasco, a 6-minute walk from San Ignacio de Velasco Cathedral, Hotel Tierra Linda has accommodations with an outdoor swimming pool, free private parking, a garden and a... Very helpful staff. Very clean and comfortable and a short walk from centre. Breakfast had a good choice of food.

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9.6
Exceptional
26 reviews
Price from
$36
per night

Located in Santa Cruz de la Sierra, a 4-minute walk from Güembé Biocentre and Guazú Ivaga Park, HOTEL OSHO has accommodations with an outdoor swimming pool, free private parking, a fitness center and... The room was super nice with great views. The room was really clean and the room was stocked up nicely with cold beer when I arrived.

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8.4
Very Good
661 reviews
Price from
$76
per night

Located in Santa Cruz de la Sierra, 984 feet from 24th of September Metropolitan Plaza, Hotel Viru Viru 1 provides accommodations with a restaurant, private parking, an outdoor swimming pool and a... Great location. Nice swimming pool. Cold AC for rooms

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8
Very Good
179 reviews
Price from
$31
per night

Hotels with extra health and safety measures

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